SANDALORE CAS#65113-99-7

  1. Authentic Sandalwood-Like Fragrance: Sandalore emits a pleasant scent that closely mimics natural sandalwood, rendering it highly suitable for application in perfumes, emollients, and skin cleansing products.

  2. Activation of Skin Olfactory Receptors: As an agonist of the cutaneous olfactory receptor OR2AT4, Sandalore induces robust calcium (Ca²⁺) signaling responses in human keratinocytes.

  3. Promotion of Skin Cell Regeneration: Sustained stimulation with Sandalore boosts keratinocyte proliferation and migration, facilitating the faster regeneration of keratinocyte monolayers.

  4. Enhanced Epidermal Wound Healing Potential: Distinct from natural sandalwood oil and other synthetic sandalwood odorants, Sandalore notably enhances epidermal "wound healing" in human skin organ cultures, showcasing unique skin-repair capabilities.

Products Description of SANDALORE CAS#65113-99-7


Sandalore is a synthetic sandalwood aroma compound that features a scent highly similar to natural sandalwood, which makes it extensively applied in perfumes, emollients, and skin cleansing formulations. Along with its related compound brahmanol, Sandalore has been confirmed to act as an agonist of the cutaneous olfactory receptor OR2AT4, and can trigger significant calcium (Ca²⁺) signaling in cultured human keratinocytes. Long-term contact of keratinocytes with Sandalore accelerates cell proliferation and migration, and also promotes the regeneration of keratinocyte monolayers in in-vitro wound scratch models, suggesting improved epidermal "wound healing" in human skin organ cultures. Natural sandalwood oil and other synthetic sandalwood fragrances, however, show no such effects.

SANDALORE CAS#65113-99-7

 

SANDALORE Chemical Properties

Boiling point 275.8±9.0 °C(Predicted)
Density 0.895-0.904
Refractive index 1.4700-1.4760
Fp >100°C
Storage temp. Refrigerator
Solubility DMSO, Methanol, Pyridine
Pka15.09±0.20(Predicted)
Form Oil
Color Clear Colourless
Odorat 100.00 %. sweet sandalwood woody waxy greasy creamy amyris
Odor Typewoody
LogP4.587 (est)
EPA Substance Registry System3-Cyclopentene-1-butanol, .alpha.,.beta.,2,2,3-pentamethyl- (65113-99-7)

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