2-Bromo-2-nitro-1,3-propanediol CAS#52-51-7

1.Good Solubility in Multiple Solvents – It is readily soluble in water, ethanol, propylene glycol, and ethyl acetate, ensuring versatile formulation compatibility.

2.Moderate Thermal Stability – The compound has a defined melting point range of 122–130°C, indicating stable physical properties.

3.Limited Oil and Organic Solvent Solubility – It is only slightly soluble in oil and sparingly soluble in solvents such as chloroform and acetone, supporting controlled application behavior.

4.High Applicability in Formulations – Its balanced solubility profile makes it suitable for use in antibacterial and related chemical formulations.

Products Description

Lopol, whose chemical name is 2‑bromo‑2‑nitro‑1,3‑propanediol and is alternatively named bromonitrol or antibacterial alcohol, appears as white crystals and has a melting‑point range of 122‑130°C.

It dissolves easily in water, ethanol, propylene glycol and ethyl acetate, shows limited solubility in oils, and is barely soluble in solvents including chloroform and acetone

Properties

 

Density1.91
Melting point124-129℃
Boiling point358 °C at 760 mmHg
Refractive index1.574
Flash Point170.3 °C
Vapour Pressure0.0±1.8 mmHg at 25°C
Precise Quality198.948
PSA86.28
logP-0.1379
SolubilityH2O: soluble100mg/mL, clear, colorless to faintly yellow
AppearanceWhite to slightly yellow crystals or crystalline powder
StorageAmbient temperatures.
Chemical Propertiesoff-white crystalline powder
Physical PropertiesColorless, white, or pinkish crystals with a slight phenolic odor. On exposure to air it slowlybecomes light brown.
Color/FormWhite to yellow
Contact AllergensBronopol is a preservative sometimes considered as aformaldehyde releaser. It was reported to be an allergenin cosmetics, cleaning agents, dairy workers, and alubricant jelly used for ultrasound examination.
DecompositionThe substance decomposes on heating or on burning producing toxic and corrosive fumes, including hydrogen bromide and nitrogen oxides.
OdorOdorless
pKa12.02±0.10(Predicted)
Water Solubility25 g/100 mL (22 oC)
Spectral PropertiesMASS: 75372 (NIST/EPA/MSDC Mass Spectral Database, 1990 version); 1023 Wiley
StabilityStable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.
StorageTempInert atmosphere,Room Temperature

2-Bromo-2-nitro-1,3-propanediol CAS#52-51-7

 

 

Product Application

Bropol exhibits potent activity against a wide spectrum of phytopathogenic bacteria and is primarily employed for seed dressing.

Thanks to its broad‑spectrum bactericidal performance, it has served as a disinfectant within the pharmaceutical sector dating back to the 1960s. As the cosmetics industry expanded swiftly, its favorable water solubility and robust antimicrobial capacity also made it a popular preservative for cosmetic formulations.

Over recent years, Bropol has found rising adoption across many fields: animal feed, coatings, fur conservation, circulating water sterilization for air‑conditioning systems, biocidal treatment for oilfield injected water, as well as sanitization for aircraft, vehicles and vessels, which drives steady expansion of its market demand.

 

2-Bromo-2-nitro-1,3-propanediol CAS#52-51-7

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