Product Details
4-Aminobutyric acid is applied in biochemical studies and clinical medicine for the management of illnesses associated with hepatic coma and cerebrovascular diseases. As a pharmaceutical raw material intermediate, it assists in decreasing blood lipid levels, which makes it ideal for the management and prophylaxis of diverse forms of hepatic coma. It can also address diseases such as poliomyelitis and cerebral hemorrhage, and act as an antidote against gas intoxication. Furthermore, it exerts functions in biochemical research and organic synthesis. 4-Aminobutyric acid decreases blood ammonia concentration and accelerates cerebral metabolism, rendering it efficacious in the treatment of hepatic coma, coma resulting from stroke sequelae, cerebral arteriosclerosis, head injury sequelae, uremia, and gas poisoning. It functions as a primary inhibitory neurotransmitter within the central nervous system, stimulates GABAA and GABAB receptors, and enhances chloride ion permeability.

Parameters
1. Names and Identifiers
| Name | 4-Aminobutyric acid |
| CAS | No.56-12-2 |
| CID | 119 |
| EINECS(EC#) | 200-258-6 |
| Molecular Formula | C4H9NO2 (isomer) |
| Inchi | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
| InChIkey | BTCSSZJGUNDROE-UHFFFAOYSA-N |
| Canonical Smiles | C(CC(=O)O)CN |
| Isomers Smiles | C(CC(=O)O)CN |
2. Properties
| Density | 1.2300 (estimate) |
| Melting point | 195?°C (dec.)(lit.) |
| Boiling point | 248oC at 760 mmHg |
| Refractive index | 1.4650 (estimate) |
| Flash Point | 103.8oC |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Precise Quality | 103.063 |
| PSA | 63.32 |
| logP | 0.5102 |
| Solubility | H2O: 1?M at?20?°C, clear, colorless |
| Appearance | H2O: 1?M at?20?°C, clear, colorless |
| Storage | Ambient temperatures. |
| Chemical Properties | White, powdery solid; savory, meat-like aroma |
| Color/Form | White to almost white |
| PKa | 4.031(at 25℃) |
| Water Solubility | H2O: 1?M at?20?°C, clear, colorless | SOLUBLE |
| Stability | Stable under normal temperatures and pressures. |
| StorageTemp | Store at RT. |
Application
4-Aminobutyric acid acts as a pharmaceutical raw material intermediate that can decrease blood lipid levels, rendering it efficient in the treatment and prophylaxis of multiple forms of hepatic coma. It may also be employed in the management of poliomyelitis and cerebral hemorrhage, as well as function as an antidote to gas poisoning. Moreover, it is broadly applied in biochemical research and organic synthesis.
This substance lowers blood ammonia content and boosts cerebral metabolic activity. It is advantageous for the intervention of various hepatic coma and coma induced by stroke sequelae, cerebral arteriosclerosis, head injury sequelae, uremia, and gas poisoning.
As a key inhibitory neurotransmitter in the brain, it functions as an agonist at GABAA and GABAB receptors, improving chloride (Cl−) ion permeability.


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