Product Details
4-Fluorobenzaldehyde (CAS#459-57-4) serves as an important building block in a variety of organic synthesis routes. This product is usually a colorless or light yellow liquid with a characteristic aromatic scent. Since it contains a highly reactive aldehyde group, it can smoothly participate in a series of common reactions such as oxidation, reduction and condensation. Moreover, the fluorine atom in its molecular structure brings special chemical activity, which allows it to act as an important reaction center in the preparation of numerous target compounds.
Parameters
| Melting point | -10 °C (lit.) |
| Boiling point | 181 °C/758 mmHg (lit.) |
| density | 1.157 g/mL at 25 °C (lit.) |
| vapor pressure | 19 hPa (70 °C) |
| refractive index | n20/D 1.521(lit.) |
| Fp | 134 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform, Methanol |
| form | Liquid |
| color | Clear colorless to yellow |
| Specific Gravity | 1.157 |
| Water Solubility | IMMISCIBLE |
| Sensitive | Air Sensitive |
| BRN | 385857 |
| Stability: | Air Sensitive |
| InChIKey | UOQXIWFBQSVDPP-UHFFFAOYSA-N |
| CAS DataBase Reference | 459-57-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 4-fluoro-(459-57-4) |
| EPA Substance Registry System | Benzaldehyde, 4-fluoro- (459-57-4) |
Safety Information
Hazard Codes | Xi,F |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39-36/37/39-27 |
RIDADR | UN 1989 3/PG 3 |
WGK Germany | 2 |
F | 9-23 |
Hazard Note | Flammable |
TSCA | T |
HazardClass | 3.2 |
PackingGroup | III |
HS Code | 29130000 |
Application
4-Fluorobenzaldehyde is a fluorine-substituted analog of benzaldehyde, which exhibits remarkable inhibitory activity on mushroom tyrosinase.It is applied in the preparation of pyrazolopyridine analogs that function as mitogen-activated protein kinase (MAPK) inhibitors.Moreover, it acts as a critical building block for the manufacturing of diverse pharmaceutical active ingredients.
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