Tolylene-2,4-diisocyanate CAS#584-84-9

  1. Moderate Stability with Environmental Sensitivity

    The product maintains structural stability under standard storage environments, but degradation can be triggered by moisture, elevated temperature and UV irradiation; strict storage control is essential.

  2. Broad Miscibility with Organic Media

    Miscible in all proportions with ether, acetone, benzene and multiple other organic solvents.

  3. Elevated Reaction Activity

    Capable of rapid chemical reaction with all active hydrogen-bearing compounds, serving as a critical raw material for polymer synthesis.

  4. Toxicological Handling Requirements

    The material poses toxic risks at high exposure levels; standardized safety operation procedures must be followed to prevent skin, respiratory and eye contact.

Toluene-2,4-diisocyanate appears as a transparent colorless liquid under standard atmospheric conditions and exhibits strong moisture sensitivity. Despite its baseline chemical stability, hydrolysis will occur upon exposure to humidity. Storage requirements: cool, dry, well-ventilated space, isolated from direct solar radiation.

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Melting point 

20-22 °C(lit.)

Boiling point 

124-126 °C18 mm Hg(lit.)

density 

1.225 g/mL at 25 °C

vapor density 

6 (vs air)

vapor pressure 

0.03 mm Hg ( 25 °C)

refractive index 

n20/D 1.568(lit.)

Fp 

250 °F

storage temp. 

2-8°C

solubility 

Miscible with ether, acetone, benzene, carbontetrachloride and chlorobenzene.

form 

Liquid

Specific Gravity

1.225

color 

Colorless

Odor

Sharp, pungent odor detectable at 0.02 to 0.4 ppm

explosive limit

9.5%

Water Solubility 

reacts

Sensitive 

Moisture Sensitive

Merck 

14,9530

BRN 

744602

Exposure limits

TLV-TWA 0.0355 mg/m3 (0.005 ppm) (ACGIH and NIOSH); STEL or ceiling/10 min 0.142 mg/m3 (0.02 ppm) (ACGIH, NIOSH, and OSHA); IDLH 71 mg/m3 (10 ppm) (NIOSH).

Stability:

Stable, but decomposes in the presence of moisture. Also heat and light sensitive. Readily polymerizes in contact with base. Reacts with compounds containing active hydrogen. Incompatible with strong oxidizing agents. Corrodes some copper and aluminium alloys.

InChIKey

DVKJHBMWWAPEIU-UHFFFAOYSA-N

LogP

3.43 at 22℃

CAS DataBase Reference

584-84-9(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 2,4-diisocyanato-1-methyl-(584-84-9)

EPA Substance Registry System

Toluene-2,4-diisocyanate (584-84-9)

 Safety Information

Hazard Codes 

T+

Risk Statements 

26-36/37/38-40-42/43-52/53

Safety Statements 

23-36/37-45-61

RIDADR 

UN 2078 6.1/PG 2

WGK Germany 

2

RTECS 

CZ6300000

10-21

Autoignition Temperature

>619 °C

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29291010

Hazardous Substances Data

584-84-9(Hazardous Substances Data)

Toxicity

Acute oral LD50 for rats 5,800 mg/kg, wild birds 100 mg/kg (quoted, RTECS, 1985).

IDLA

2.5 ppm

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